{"id":26,"date":"2016-02-06T17:20:53","date_gmt":"2016-02-06T16:20:53","guid":{"rendered":"http:\/\/serek.panel.szn.pl\/machalinski\/?page_id=26"},"modified":"2020-01-12T21:52:30","modified_gmt":"2020-01-12T20:52:30","slug":"badania","status":"publish","type":"page","link":"https:\/\/machalinski.pl\/naukowo\/badania\/","title":{"rendered":"Badania"},"content":{"rendered":"\n<p> Badania naukowe s\u0105 integraln\u0105 cz\u0119\u015bci\u0105 pracy akademickiej. Znaczn\u0105 cz\u0119\u015b\u0107 tej formy aktywno\u015bci na PUM po\u015bwi\u0119ci\u0142em prowadzeniu prac badawczych nad kom\u00f3rkami macierzystymi. <\/p>\n\n\n\n<p> Ich zasadniczym celem by\u0142o zawsze d\u0105\u017cenie do wykorzystania wynik\u00f3w\u00a0bada\u0144 w terapiach chor\u00f3b \u2013 medycyna powinna mie\u0107 zawsze wymiar empiryczny. W ostatnim czasie kierowana przeze mnie Katedra Fizjopatologii i Zak\u0142ad Patologii Og\u00f3lnej zasadniczo skupia\u0142 si\u0119 wok\u00f3\u0142 kilku<strong> wiod\u0105cych zagadnie\u0144 badawczych<\/strong>. <\/p>\n\n\n<p style=\"text-align: right;\"><button class=\"toggler\">Wi\u0119cej&#8230;<\/button><\/p>\n<ul class=\"hidden\">\n<li>Biologia kom\u00f3rek macierzystych \u2013 mechanizmy proliferacji i r\u00f3\u017cnicowania pod wp\u0142ywem interakcji z czynnikami troficznymi i hormonalnymi.<\/li>\n<li>Terapia kom\u00f3rkowo-genowa jako terapeutyczna metoda adjuwantowa w leczeniu chor\u00f3b degeneracyjnych i uwarunkowanych genetycznie.<\/li>\n<li>Rozw\u00f3j in\u017cynierii genetycznej i nanotechnologii dla cel\u00f3w terapii kom\u00f3rkowo-genowej.<\/li>\n<li>Czynniki wzrostowe, cytokiny i chemokiny jako biomarkery chor\u00f3b neurodegeneracyjnych i cywilizacyjnych.<\/li>\n<li>Rola czynnik\u00f3w neurotroficznych w patologii i regeneracji uk\u0142adu nerwowego.<\/li>\n<li>Opracowanie i optymalizacja metod regeneracji wrodzonych i nabytych defekt\u00f3w siatk\u00f3wki oka.<\/li>\n<li>Opracowanie strategii terapeutycznych z zastosowaniem kom\u00f3rek macierzystych i progenitorowych wykorzystywanych do leczenia pacjent\u00f3w cierpi\u0105cych na choroby uk\u0142adu kr\u0105\u017cenia oraz choroby neurodegeneracyjne, w tym na choroby siatk\u00f3wki oka (AMD) oraz stwardnienie zanikowe boczne (ALS).<\/li>\n<li>Molekularne mechanizmy leukemogenezy i angiogenezy w przebiegu bia\u0142aczek i ch\u0142oniak\u00f3w.<\/li>\n<\/ul>\n\n\n<figure class=\"wp-block-gallery columns-5 is-cropped wp-block-gallery-1 is-layout-flex wp-block-gallery-is-layout-flex\"><ul class=\"blocks-gallery-grid\"><li class=\"blocks-gallery-item\"><figure><a href=\"https:\/\/machalinski.pl\/wp-content\/uploads\/2020\/01\/o15_023-mini.jpg\" rel=\"lightbox[26]\"><img decoding=\"async\" loading=\"lazy\" width=\"1024\" height=\"683\" src=\"https:\/\/machalinski.pl\/wp-content\/uploads\/2020\/01\/o15_023-mini-1024x683.jpg\" alt=\"\" data-id=\"672\" data-full-url=\"https:\/\/machalinski.pl\/wp-content\/uploads\/2020\/01\/o15_023-mini.jpg\" data-link=\"https:\/\/machalinski.pl\/obrazowo\/o15_023-mini\/\" class=\"wp-image-672\" srcset=\"https:\/\/machalinski.pl\/wp-content\/uploads\/2020\/01\/o15_023-mini-1024x683.jpg 1024w, https:\/\/machalinski.pl\/wp-content\/uploads\/2020\/01\/o15_023-mini-300x200.jpg 300w, https:\/\/machalinski.pl\/wp-content\/uploads\/2020\/01\/o15_023-mini-768x513.jpg 768w, https:\/\/machalinski.pl\/wp-content\/uploads\/2020\/01\/o15_023-mini-1536x1025.jpg 1536w, https:\/\/machalinski.pl\/wp-content\/uploads\/2020\/01\/o15_023-mini.jpg 1798w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/a><\/figure><\/li><li class=\"blocks-gallery-item\"><figure><a href=\"https:\/\/machalinski.pl\/wp-content\/uploads\/2019\/12\/a01_039-mini.jpg\" rel=\"lightbox[26]\"><img decoding=\"async\" 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href=\"https:\/\/machalinski.pl\/wp-content\/uploads\/2019\/12\/n03_050-mini-X.jpg\" rel=\"lightbox[26]\"><img decoding=\"async\" loading=\"lazy\" width=\"1000\" height=\"1000\" src=\"https:\/\/machalinski.pl\/wp-content\/uploads\/2019\/12\/n03_050-mini-X.jpg\" alt=\"\" data-id=\"542\" data-full-url=\"https:\/\/machalinski.pl\/wp-content\/uploads\/2019\/12\/n03_050-mini-X.jpg\" data-link=\"https:\/\/machalinski.pl\/naukowo\/badania\/n03_050-mini-x\/\" class=\"wp-image-542\" srcset=\"https:\/\/machalinski.pl\/wp-content\/uploads\/2019\/12\/n03_050-mini-X.jpg 1000w, https:\/\/machalinski.pl\/wp-content\/uploads\/2019\/12\/n03_050-mini-X-300x300.jpg 300w, https:\/\/machalinski.pl\/wp-content\/uploads\/2019\/12\/n03_050-mini-X-150x150.jpg 150w, https:\/\/machalinski.pl\/wp-content\/uploads\/2019\/12\/n03_050-mini-X-768x768.jpg 768w, https:\/\/machalinski.pl\/wp-content\/uploads\/2019\/12\/n03_050-mini-X-270x270.jpg 270w, https:\/\/machalinski.pl\/wp-content\/uploads\/2019\/12\/n03_050-mini-X-230x230.jpg 230w\" sizes=\"(max-width: 1000px) 100vw, 1000px\" \/><\/a><\/figure><\/li><li class=\"blocks-gallery-item\"><figure><a href=\"https:\/\/machalinski.pl\/wp-content\/uploads\/2016\/02\/082.jpg\" rel=\"lightbox[26]\"><img decoding=\"async\" loading=\"lazy\" width=\"1024\" height=\"684\" src=\"https:\/\/machalinski.pl\/wp-content\/uploads\/2016\/02\/082-1024x684.jpg\" alt=\"\" data-id=\"370\" data-full-url=\"https:\/\/machalinski.pl\/wp-content\/uploads\/2016\/02\/082.jpg\" data-link=\"https:\/\/machalinski.pl\/obrazowo\/attachment\/082\/\" class=\"wp-image-370\" srcset=\"https:\/\/machalinski.pl\/wp-content\/uploads\/2016\/02\/082-1024x684.jpg 1024w, https:\/\/machalinski.pl\/wp-content\/uploads\/2016\/02\/082-300x200.jpg 300w, https:\/\/machalinski.pl\/wp-content\/uploads\/2016\/02\/082-768x513.jpg 768w, https:\/\/machalinski.pl\/wp-content\/uploads\/2016\/02\/082.jpg 1498w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/a><\/figure><\/li><li class=\"blocks-gallery-item\"><figure><a href=\"https:\/\/machalinski.pl\/wp-content\/uploads\/2016\/02\/124-X.jpg\" rel=\"lightbox[26]\"><img decoding=\"async\" loading=\"lazy\" width=\"1000\" height=\"1000\" src=\"https:\/\/machalinski.pl\/wp-content\/uploads\/2016\/02\/124-X.jpg\" alt=\"\" data-id=\"429\" data-full-url=\"https:\/\/machalinski.pl\/wp-content\/uploads\/2016\/02\/124-X.jpg\" data-link=\"https:\/\/machalinski.pl\/naukowo\/badania\/124-x\/\" class=\"wp-image-429\" srcset=\"https:\/\/machalinski.pl\/wp-content\/uploads\/2016\/02\/124-X.jpg 1000w, https:\/\/machalinski.pl\/wp-content\/uploads\/2016\/02\/124-X-150x150.jpg 150w, https:\/\/machalinski.pl\/wp-content\/uploads\/2016\/02\/124-X-300x300.jpg 300w, https:\/\/machalinski.pl\/wp-content\/uploads\/2016\/02\/124-X-768x768.jpg 768w, https:\/\/machalinski.pl\/wp-content\/uploads\/2016\/02\/124-X-270x270.jpg 270w, 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Znaczn\u0105 cz\u0119\u015b\u0107 tej formy aktywno\u015bci na PUM po\u015bwi\u0119ci\u0142em prowadzeniu prac badawczych nad kom\u00f3rkami macierzystymi.<\/p>\n","protected":false},"author":1,"featured_media":186,"parent":24,"menu_order":1,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"_links":{"self":[{"href":"https:\/\/machalinski.pl\/wp-json\/wp\/v2\/pages\/26"}],"collection":[{"href":"https:\/\/machalinski.pl\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/machalinski.pl\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/machalinski.pl\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/machalinski.pl\/wp-json\/wp\/v2\/comments?post=26"}],"version-history":[{"count":14,"href":"https:\/\/machalinski.pl\/wp-json\/wp\/v2\/pages\/26\/revisions"}],"predecessor-version":[{"id":777,"href":"https:\/\/machalinski.pl\/wp-json\/wp\/v2\/pages\/26\/revisions\/777"}],"up":[{"embeddable":true,"href":"https:\/\/machalinski.pl\/wp-json\/wp\/v2\/pages\/24"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/machalinski.pl\/wp-json\/wp\/v2\/media\/186"}],"wp:attachment":[{"href":"https:\/\/machalinski.pl\/wp-json\/wp\/v2\/media?parent=26"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}